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Thalidomide-O-amido-C6-NH2 hydrochloride
CAS No. 2376990-31-5
Thalidomide-O-amido-C6-NH2 hydrochloride( —— )
Catalog No. M27019 CAS No. 2376990-31-5
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. It can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 338 | Get Quote |
|
| 10MG | 501 | Get Quote |
|
| 25MG | 807 | Get Quote |
|
| 50MG | 1107 | Get Quote |
|
| 100MG | 1485 | Get Quote |
|
| 500MG | 2961 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameThalidomide-O-amido-C6-NH2 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionThalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. It can be used in the synthesis of PROTACs.
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DescriptionThalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. It can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorP450
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Research Area——
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Indication——
Chemical Information
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CAS Number2376990-31-5
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Formula Weight466.92
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Molecular FormulaC21H27ClN4O6
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.NCCCCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Levron, J.C., et al. Pharmacokinetic study of 2,3-dichloro 4- (2-thienyl keto14C) phenoxyacetic acid (tienilic acid) in animals. European Journal of Drug Metabolism and Pharmacokinetics 2, 107–120 (1977).
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